Epirus, like the region as a whole, is rugged and mountainous.It comprises the land of the ancient Molossians and Thesprotians and a small part of the land of the Chaonians the greater part being in Southern Albania. It is largely made up of mountainous ridges, part of the Dinaric Alps. The region's highest spot is on Mount Smolikas, at an altitude of 2.637 metres above sea level. In the east, the Pindus Mountains that form the spine of mainland Greece separate Epirus from Macedonia and Thessaly. Most of Epirus lies on the windward side of the Pindus. The winds from the Ionian Sea offer the region more rainfall than any other part of Greece.The Vikos-Aoos and Pindus National Parks are situated in the Ioannina Prefecture of the region. Both areas have imposing landscapes of dazzling beauty as well as a wide range of fauna and flora. The climate of Epirus is mainly alpine. The vegetation is made up mainly of coniferous species. The animal life is especially rich in this area and includes, among other species, bears, wolves, foxes, deer and lynxes.

Epirus is divided into four regional units (formerly prefectures, nomoi), which are further subdivided into municipalities (dimoi). The regional units are: Thesprotia, Ioannina, Arta and Preveza.

The administrative division of the Epirus region in municipalities. In shades of yellow, the regional unit of Thesprotia, in red, Ioannina, in blue, Preveza and in green, ArtaFrom January 2011, according to the reform introduced by the Kallikratis Programme (Act 3852/2010) the prefectures were abolished and replaced by regional units. The former municipalities and communities were re-structured to form only 18 new municipalities.

Epirus has few resources and its rugged terrain makes agriculture difficult. Sheep and goat pastoralism have always been an important activity in the region (Epirus provides more than 45% of meat to the Greek market) but there seems to be a decline in recent years. Tobacco is grown around Ioannina, and there is also some farming and fishing, but most of the area's food must be imported from more fertile regions of Greece. Epirus is home to a number of the country's most famous dairy products' brands, which produce feta cheese among others. An important area of the economy is also tourism, especially eco-tourism. The natural beauty of the area, as well as the picturesque villages, have made Epirus a strong tourist attraction.

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